KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1S
All Species:
16.97
Human Site:
Y399
Identified Species:
53.33
UniProt:
Q13698
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13698
NP_000060.2
1873
212350
Y399
G
S
D
T
E
S
L
Y
E
I
A
G
L
N
K
Chimpanzee
Pan troglodytes
XP_525018
1874
212521
Y399
G
S
D
T
E
S
L
Y
E
I
A
G
L
N
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848685
1876
212961
Y399
G
S
D
T
E
S
L
Y
E
I
E
G
L
N
K
Cat
Felis silvestris
Mouse
Mus musculus
Q02789
1880
213241
Y399
G
S
D
T
E
S
L
Y
E
I
E
G
L
N
K
Rat
Rattus norvegicus
P22002
2169
243464
E507
E
T
E
S
V
N
T
E
N
V
A
G
G
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
M487
S
S
N
K
H
A
S
M
P
T
S
E
T
E
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001139622
1777
202411
Y409
G
S
E
T
E
T
L
Y
E
L
D
I
L
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24270
2516
276682
G947
M
D
S
T
E
N
L
G
E
E
M
P
E
V
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
N.A.
91.5
N.A.
90.9
58
N.A.
N.A.
56.8
N.A.
67.8
N.A.
40.5
N.A.
N.A.
N.A.
Protein Similarity:
100
98.8
N.A.
94.9
N.A.
94.7
69.6
N.A.
N.A.
68.5
N.A.
78.9
N.A.
52.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
13.3
N.A.
N.A.
6.6
N.A.
66.6
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
53.3
N.A.
N.A.
26.6
N.A.
86.6
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
13
0
0
0
0
38
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
50
0
0
0
0
0
0
0
13
0
0
13
0
% D
% Glu:
13
0
25
0
75
0
0
13
75
13
25
13
13
13
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
63
0
0
0
0
0
0
13
0
0
0
63
13
0
0
% G
% His:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
50
0
13
0
0
13
% I
% Lys:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
63
% K
% Leu:
0
0
0
0
0
0
75
0
0
13
0
0
63
0
0
% L
% Met:
13
0
0
0
0
0
0
13
0
0
13
0
0
0
0
% M
% Asn:
0
0
13
0
0
25
0
0
13
0
0
0
0
63
0
% N
% Pro:
0
0
0
0
0
0
0
0
13
0
0
13
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
13
75
13
13
0
50
13
0
0
0
13
0
0
0
13
% S
% Thr:
0
13
0
75
0
13
13
0
0
13
0
0
13
0
0
% T
% Val:
0
0
0
0
13
0
0
0
0
13
0
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
63
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _